Publications
A complete list of publications can be assessed here.
Inhibition of mevalonate metabolism by statins augments the immunoregulatory phenotype of vascular endothelial cells and inhibits the costimulation of CD4+ T cells
T cell-Specific Adaptor Protein regulates mitochondrial function and CD4+ T regulatory cell activity in vivo following transplantation
Johannes Wedel, Maria P Stack, Tatsuichiro Seto, Matthew M Sheehan, Evelyn A Flynn, Isaac E Stillman, Sek Won Kong, Kaifeng Liu, David M Briscoe
DEPTOR modulates activation responses in CD4+ T cells and enhances immunoregulation following transplantation
Johannes Wedel, Sarah Bruneau, Kaifeng Liu, Sek Won Kong, Peter T Sage, David M Sabatini, Mathieu Laplante, David M Briscoe
The intragraft microenvironment as a central determinant of chronic rejection or local immunoregulation/tolerance
Johannes Wedel, Hironao Nakayama, Nora M Kochupurakkal, Josephine Koch, Michael Klagsbrun, Diane R Bielenberg, David M Briscoe
Netrin-1 augments chemokinesis in CD4+ T cells in vitro and elicits a proinflammatory response in vivo
Leo Boneschansker, Hironao Nakayama, Michele Eisenga, Johannes Wedel, Michael Klagsbrun, Daniel Irimia, David M Briscoe
Pharmacological inhibition of vanin activity attenuates transplant vasculopathy in rat aortic allografts
Johannes Wedel, Patrick A M Jansen, Peter N M Botman, Floris P J T Rutjes, Joost Schalkwijk, Jan-Luuk Hillebrands
N-octanoyl dopamine attenuates the development of transplant vasculopathy in rat aortic allografts via smooth muscle cell protective mechanisms
Johannes Wedel, Maximilia C Hottenrott, Marian Bulthuis, Sippie Huitema, Benito A Yard, Jan-Luuk Hillebrands
Translational implications of endothelial cell dysfunction in association with chronic allograft rejection
Sarah Bruneau, Johannes Wedel, Fadi Fakhouri, Hironao Nakayama, Leo Boneschansker, Daniel Irimia, Kevin P Daly, David M Briscoe
N-acyl dopamine derivates as lead compound for implementation in transplantation medicine
Johannes Wedel*, Prama Pallavi*, Eleni Stamellou, Benito A Yard (*co-first)
Chronic allograft rejection: a fresh look
Johannes Wedel, Sarah Bruneau, Nora Kochupurakkal, Leo Boneschansker, David M Briscoe
N-octanoyl dopamine transiently inhibits T cell proliferation via G1 cell-cycle arrest and inhibition of redox-dependent transcription factors
Johannes Wedel, Maximillia C Hottenrott, Eleni Stamellou, Annette Breedijk, Charalambos Tsagogiorgas, Jan-Luuk Hillebrands, Benito A Yard